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Biofluid Mechanics Lab in the ICM

The task of the laboratory, founded 1985 by Klaus Affeld, is to apply engineering methods to problems of medicine. The focus here is on fluid mechanics in medicine. The development of new medical products and measurement techniques is just as much a part of this as the use of numerical methods. The laboratory is part of the Institute for Imaging Science and Computational Modelling in Cardiovascular Medicine (ICM) at Charité Center 11 for Cardiovascular Diseases.

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Research areas of the Biofluid Mechanics Lab

Development and flow optimisation of artificial organs

  • Heart valves
  • Heart support systems
  • Blood pumps

Haemodynamics and mass transport in natural vessels and capillary networks

  • Computational Fluid Dynamics (CFD)
  • Fluid Structure Interaction (FSI)
  • experimental blood flow simulation (alginate beads)
  • experimental and numerical blood damage
  • experimental and numerical platelet attachment

Development of measurement technology, bioreactors and flow visualisation methods

  • Particle Image Velocimetry (PIV, near wall PIV)
  • Colour erosion method
  • Colour washout method
  • Low-stress non-invasive blood pressure measurement
  • Bioreactor for antibiotic resistance prevention through treatment simulation