New technical and clinical ways to realize a cost-oriented VAD therapy II

Approximately one million patients worldwide are in the final stage of heart failure. Heart transplantation is the last possible form of therapy for these patients, although only about 3,000 donor hearts are available worldwide every year and this number is decreasing. Accordingly, mechanical heart and circulatory support systems, so-called VADs (Ventricular Assist Devices) or artificial hearts bridge the waiting time for a transplant or are increasingly used as a long-term alternative to heart transplantation. In certain cases, a recovery of the heart using a VAD can also be observed, which allows subsequent weaning and explantation of the VAD.

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Aim

Berlin Heart INCOR und Konzeptstudie der Next Generation Pump

The overall objective of the project is to further investigate the existing functional model for the future development of a cardiac support system for the chronic treatment of terminal heart failure. This project is carried out in cooperation with Berlin Heart GmbH. The Next Generation Pump (NGP) system is designed to

  1. improve clinical outcomes of VAD therapy in terms of life expectancy, complication rate, hemocompatibility and quality of life, and
  2. reduce therapy costs as the sum of system costs, costs of implantation and follow-up treatment as well as costs of aftercare.

Methods

  • Numerical and experimental modelling of critical points in NGP
  • Experimental investigation and modelling of blood damage
  • Design modification of the NGP design

Cooperation partners

  • Berlin Heart GmbH

Funding

This project was co-financed by the European Regional Development Fund (ERDF).