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Veröffentlichungen

Hier finden Sie die Veröffentlichungen des Instituts für Kardiovaskuläre Computer-assistierte Medizin seit 2017.

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Veröffentlichungen 2023

27

Manini C, Nemchyna O, Akansel S, Walczak L, Tautz L, Kolbitsch C, Falk V, Sündermann S, Kühne T, Schulz-Menger J, Hennemuth A.A simulation-based phantom model for generating synthetic mitral valve image data-application to MRI acquisition planning.Int J Comput Assist Radiol Surg. 2023 Sep 7.

26

Brüning J, Yevtushenko P, Schlief A, Jochum T, van Gijzen L, Meine S, Romberg J, Kuehne T, Arndt A and Goubergrits L.In-silico enhanced animal study of pulmonary artery pressure sensors: assessing hemodynamics using computational fluid dynamics.Front. Cardiovasc. Med. 10:1193209.

25

Bierewirtz T, Narayanaswamy K, Giuffrida R, Rese T, Bortis D, Zimpfer D, Kolar J, Kertzscher U, Granegger M.A Novel Pumping Principle for a Total Artificial Heart.IEEE Trans Biomed Eng. 2023 Aug 21;PP.

24

Ivantsits M, Pfahringer B, Huellebrand M, Walczak L, Tautz L, Nemchyna O, Akansel S, Kempfert J, Suendermann S, Hennemuth A.3D Mitral Valve Surface Reconstruction from 3D TEE via Graph Neural Networks.Conference paper.28 January 2023.

23

Krefting D, Anton G, Chaplinskaya-Sobol I, Hanss S, Hoffmann W, Hopff S, Kraus M, Lorbeer R, Lorenz-Depiereux B, Illig T, Schaefer C, Schaller J, Stahl D, Valentin H, Heuschmann P, Vehreschild J.The Importance of Being FAIR and FAST - The Clinical Epidemiology and Study Platform of the German Network University Medicine (NUKLEUS).Stud Health Technol Inform. 2023 May 18;302:93-97.

22

Heyder R, NUM Coordination Office, NUKLEUS Study Group, NUM-RDP Coordination, RACOON Coordination, AKTIN Coordination, GenSurv Study Group.[The German Network of University Medicine: technical and organizational approaches for research data platforms]Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2023 Feb;66(2):114-125.

21

Martin-Isla C, Campello, V, Izquierdo C, Kushibar K, Sendra-Balcells C, Gkontra P, Sojoudi A, Fulton M, Arega T, Punithakumar K, Li L, Sun X, Khalil Y, Liu D, Jabbar S, Queiros S, Galati F, Mazher M, Gao Z, Beetz M, Tautz L, Galazis C, Varela M, Hullebrand M, Grau V, Zhuang X, Puig D, Zuluaga M, Mohy-Ud-Din H, Metaxas D, Breeuwer M, Geest R, Noga M, Bricq S, Rentschler M,Guala A, Petersen S, Escalera S, Palomares J, Lekadir K.Deep Learning Segmentation of the Right Ventricle in Cardiac MRI: The M&Ms Challenge.IEEE J Biomed Health Inform. 2023 Jul;27(7):3302-3313.

20

Bissell MM, Raimondi F, Ait Ali L, Allen BD, Barker AJ, Bolger A, Burris N, Carhäll CJ, Collins JD, Ebbers T, Francois CJ, Frydrychowicz A, Garg P, Geiger J, Ha H, Hennemuth A, Hope MD, Hsiao A, Johnson K, Kozerke S, Ma LE, Markl M, Martins D, Messina M, Oechtering TH, van Ooij P, Rigsby C, Rodriguez-Palomares J, Roest AAW, Roldán-Alzate A, Schnell S, Sotelo J, Stuber M, Syed AB, Töger J, van der Geest R, Westenberg J, Zhong L, Zhong Y, Wieben O, Dyverfeldt P. 4D Flow cardiovascular magnetic resonance consensus statement: 2023 updat.J Cardiovasc Magn Reson. 2023 Jul 20;25(1):40

19

Strecker C, Kopczak A, Saam T, Sepp D, Hennemuth A, Mayerhofer E, Poli S, Ziemann U, Poppert H, Schindler A, Harloff A. Carotid geometry is independently associated with complicated carotid artery plaquesFront Cardiovasc Med. 2023 Jun 12;10:1177998

18

Escher A, Thamsen B, Strauch C, Kertzscher U, Zimpfer D, Thamsen PU, Granegger M.In-Vitro Flow Validation of Third-Generation Ventricular Assist Devices: Feasibility and ChallengesASAIO J. 2023 Jul 8.

17

Hadler, T., Ammann, C., Wetzl, J., Viezzer, D., Gröschel, J., Fenski, M., Abazi, E., Lange, S., Hennemuth, A., Schulz-Menger, J.Lazy Luna: Extendible software for multilevel reader comparison in cardiovascular magnetic resonance imagingComput Methods Programs Biomed. 2023 Aug;238:107615.

16

Franke, B., Schlief, A., Walczak, L., Sündermann, S., Unbehaun, A., Kempfert, J., Solowjowa,N., Kuehne, T., Goubergrits, L.Comparison of hemodynamics in biological surgical aortic valve replacement and transcatheter aortic valve implantation: An in-silico studyArtif Organs. 2023 Feb;47(2):352-360.

15

Loose, S., Solou, D., Strecker, C., Hennemuth, A., Hüllebrand, M., Grundmann, S., Asmussen, A., Treppner, M., Urbach, H., Harloff, A.Characterization of aortic aging using 3D multi-parametric MRI-long-term follow-up in a population studySci Rep. 2023 Apr 18;13(1):6285.

14

Gerevich Z, Kovács R, Liotta A, Hasam-Henderson LA, Weh L, Wallach I, Berndt N. Metabolic implications of axonal demyelination and its consequences for synchronized network activity: An in silico and in vitro study. J Cereb Blood Flow Metab. 2023 Sep;43(9):1571-1587.

13

Huellebrand M, Jarmatz L, Manini C, Laube A, Ivantsits M, Schulz-Menger J, Nordmeyer S, Harloff A, Hansmann J, Kelle S and Hennemuth A.Radiomics-based aortic flow profile characterization with 4D phase-contrast MRI Front. Cardiovasc. Med. 10:1102502.

12

Oechtering TH, Nowak A, Sieren MM, Stroth AM, Kirschke N, Wegner F, Balks M, König IR, Jin N, Graessner J, Kooijman-Kurfuerst H, Hennemuth A, Barkhausen J, Frydrychowicz A. Repeatability and reproducibility of various 4D Flow MRI postprocessing software programs in a multi-software and multi-vendor cross-over comparison study. J Cardiovasc Magn Reson. 2023 Mar 28;25(1):22

11

Samuelsson AM, Bartolomaeus TUP, Anandakumar H, Thowsen I, Nikpey E, Han J, Marko L, Finne K, Tenstad O, Eckstein J, Berndt N, Kuehne T, Kedziora S, Sultan I, Skogstrand T, Karlsen TV, Nurmi H, Forslund SK, Bollano E, Alitalo K, Muller DN, Wiig H. VEGF-B hypertrophy predisposes to transition from diastolic to systolic heart failure in hypertensive rats. Cardiovasc Res. 2023 Jul 4;119(7):1553-1567.

10

Granegger M, Escher A, Karner B, Kainz M, Schlöglhofer T, Schwingenschlögl H, Roehrich M, Karl Podesser B, Kramer AM, Kertzscher U, Laufer G, Hübler M, Zimpfer D.Feasibility of an Animal Model for Cavopulmonary Support With a Double-Outflow Pump.ASAIO J. 2023 Mar 21.

9

Reiffurth C*, Berndt N*, Lopez AG, Schoknecht K, Kovács R, Maechler M, Lambers MG, Dreier JP, Friedman A, Spies C, Liotta A. Deep isoflurane anesthesia is associated with alterations in ion homeostasis and specific Na+/K+-ATPase impairment in the rat brain.Anesthesiology. 2023 Jun 1;138(6):611-623.

8

Katz, S, Caiazzo, A, Moreau, B, Wilbrandt U, Brüning J, Goubergrits L, John V.Impact of turbulence modeling on the simulation of blood flow in aortic coarctation. Int J Numer Meth Biomed Engng. 2023;e3695.

7

Hoffmann J, Hanß S, Kraus M, Schaller J, Schäfer C, Stahl D, Anker SD, Anton G, Bahls T, Blankenberg S, Blumentritt A, Boldt LH, Cordes S, Desch S, Doehner W, Dörr M, Edelmann F, Eitel I, Endres M, Engelhardt S, Erdmann J, Eulenburg K, Falk V, Felix SB, Frank D, Franke T, Frey N, Friede T, Geidel L, Germans L, Grabmaier U, Halle M, Hausleiter J, Jakobi V, Jebran AF, Jobs A, Kääb S, Karakas M, Katus HA, Klatt A, Knosalla C, Krebser J, Landmesser U, Lee M, Lehnert K, Lesser S, Leyh K, Lorbeer R, Mach-Kolb S, Meder B, Nagel E, Nolte CH, Parwani AS, Petersmann A, Puls M, Rau H, Reiser M, Rienhoff O, Scharfe T, Schattschneider M, Scheel H, Schnabel RB, Schuster A, Schmitt B, Seidler T, Seiffert M, Stähli BE, Stas A, J Stocker T, von Stülpnagel L, Thiele H, Wachter R, Wakili R, Weis T, Weitmann K, Wichmann HE, Wild P, Zeller T, Hoffmann W, Zeisberg EM, Zimmermann WH, Krefting D, Kühne T, Peters A, Hasenfuß G, Massberg S, Sommer T, Dimmeler S, Eschenhagen T, Nauck M.The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies..Clin Res Cardiol. 2023 Mar 8.

6

Yevtushenko P, Goubergrits L, Franke B, Kuehne T and Schafstedde M. Modelling blood flow in patients with heart valve disease using deep learning: A computationally efficient method to expand diagnostic capabilities in clinical routine.Front. Cardiovasc. Med. 10:1136935.

5

Hanigk M, Burgstaller E, Latus H, Shehu N, Zimmermann J, Martinoff S, Hennemuth A, Ewert P, Stern H, Meierhofer C.Aortic wall shear stress in bicuspid aortic valve disease-10-year follow-up.Cardiovasc Diagn Ther. 2023 Feb 28;13(1):38-50.

4

Schafstedde M, Nordmeyer S. The role of androgens in pressure overload myocardial hypertrophy.Front Endocrinol (Lausanne). 2023 Feb 1;14:1112892.

3

Nordmeyer S, Kraus M, Ziehm M, Kirchner M, Schafstedde M, Kelm M, Niquet S, Stephen MM, Baczko I, Knosalla C, Schapranow MP, Dittmar G, Gotthardt M, Falcke M, Regitz-Zagrosek V, Kuehne T, Mertins P. Disease- and sex-specific differences in patients with heart valve disease: a proteome study.Life Sci Alliance. 2023 Jan 10;6(3):e202201411.

2

Kossen T, Madai VI, Mutke MA, Hennemuth A, Hildebrand K, Behland J, Aslan C, Hilbert A, Sobesky J, Bendszus M, Frey D.Image-to-image generative adversarial networks for synthesizing perfusion parameter maps from DSC-MR images in cerebrovascular disease.Front Neurol. 2023 Jan 10;13:1051397

1

Schafstedde M, Jarmatz L, Brüning J, Hüllebrandt M, Nordmeyer S, Harloff A, Hennemuth A. Population-based reference values for 4D flow MRI derived aortic blood flow parameters .Physiol Meas. 2023 Feb 3.

Veröffentlichungen 2022

47

Shahryari M, Keller S, Meierhofer D, Wallach I, Safraou Y, Guo J, Marticorena Garcia SR, Braun J, Makowski MR, Sack I and Berndt N.On the relationship between metabolic capacities and in vivo viscoelastic properties of the liver. Front. Bioeng. Biotechnol. 2023 Jan 9;10:1042711.

46

Lewin D, Van Praet KM, Nersesian G, Kelm M, Kofler M, Baumgartner M, Kempfert J, Falk V, Klein C, Unbehaun A. Transcatheter Aortic Valve Replacement in a Patient With Criss-Cross Heart. JACC Case Rep. 2022 Aug 3;4(15):934-940.

45

Ivantsits M, Goubergrits L, Kuhnigk J-M, Huellebrand M, Brüning J, Kossen T, Pfahringer B, Schaller J, Spuler A, Kuehne T, Jia Y, Li X, Shit S, Menze B, Su Z, Ma J, Nie Z, Jain K, Liu Y, Lin Y, Hennemuth A. Detection and Analysis of Cerebral Aneurysms based on X-ray Rotational Angiography - The CADA 2020 Challenge. Medical Image Analysis 2022 Apr;77:102333.

44

Hehnen F, Wendt G, Schaller J, Geus P, Villwock J, Kertzscher U, Goubergrits L. Investigation of the attachment of circulating endothelial cells to a cell probe: combined experimental and numerical study.. Adv. Eng. Mater. 2021, 24: 2101317.

43

Maifeld A, Wild J, Karlsen TV, Rakova N, Wistorf E, Linz P, Jung R, Birukov A, Gimenez-Rivera VA, Wilck N, Bartolomaeus T, Dechend R, Kleinewietfeld M, Forslund SK, Krause A, Kokolakis G, Philipp S, Clausen BE, Brand A, Waisman A, Kurschus FC, Wegner J, Schultheis M, Luft FC, Boschmann M, Kelm M, Wiig H, Kuehne T, Müller DN, Karbach S, Markó L. Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity. J Invest Dermatol. 2021 Jul 5:S0022-202X(21)01423-8.

42

Wehrum T, Dragonu I, Strecker C, Hennemuth A, Hennig J, Reinhard T, Harloff A. Influence of Pulse Wave Velocity on Atherosclerosis and Blood Flow Reversal in the Aorta: A 4-Dimensional Flow Magnetic Resonance Imaging Study in Acute Stroke Patients and Matched Controls. J Thorac Imaging. 2021 Jan 21;37(1):42-48

41

Maifeld, A., Wild, J., Karlsen, T., Rakova, N., Wistorf, E., Linz, P., Jung, R., Birukov, A., Gimenez-Rivera, V., Wilck, N., Bartolomaeus, T., Dechend, R., Kleinewietfeld, M., Forslund, S., Krause, A., Kokolakis, G., Philipp, S., Clausen, B., Brand, A., Waisman, A., Kurschus, F., Wegner, J., Schultheis, M., Luft, F., Boschmann, M., Kelm, M., Wiig, H., Kühne, T., Müller, D., Karbach, S., Markó, L.Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity.J Invest Dermatol. 2022 Jan;142(1):166-178.e

40

Hehnen, F., Wendt, G., Schaller, J., Geus, P., Villwock, J., Kertzscher, U., Goubergrits, L.Investigation of the Attachment of Circulating Endothelial Cells to a Cell Probe: Combined Experimental and Numerical Study.AEM Journal. Adv. Eng. Mater. 2022, 24, 2101317.

39

Wehrum, T., Dragonu, I., Strecker, C., Hennemuth,A., Hennig, J., Reinhard, T., Harloff, A.Influence of Pulse Wave Velocity on Atherosclerosis and Blood Flow Reversal in the Aorta: A 4-Dimensional Flow Magnetic Resonance Imaging Study in Acute Stroke Patients and Matched Controls.J Thorac Imaging. 2022 Jan 1;37(1):42-48.

38

Kossen, T., Madai, V., Mutke, M., Hennemuth, A., Hildebrand, K., Behland, J., Aslan, C., Hilbert, A., Sobesky, J., Bendszus, M., Frey, D.Image-to-image generative adversarial networks for synthesizing perfusion parameter maps from DSC-MR images in cerebrovascular disease.Front Neurol. 2023 Jan 10;13:1051397.

37

Ivantsits, M., Goubergrits, L., Kuhnigk, J., Hüllebrand, M., Bruening, J., Kossen, T., Pfahringer, B., Schaller, J., Spuler, A., Kuehne, T., Jia, Y., Li, X., Shit, S., Menze, B., Su, Z., Ma, J., Nie, Z., Jain, K., Liu, Y., Lin, Y., Hennemuth, A.Detection and analysis of cerebral aneurysms based on X-ray rotational angiography - the CADA 2020 challenge.Med Image Anal.2022 Apr;77:102333.

36

Yevtushenko, P., Goubergrits, L., Gundelwein, L., Setio, A., Ramm, H., Lamecker, H., Heimann, T., Meyer, A., Kuehne, T., Schafstedde, M.Deep Learning Based Centerline-Aggregated Aortic Hemodynamics: An Efficient Alternative to Numerical Modeling of Hemodynamicsa. IEEE J Biomed Health Inform.2022 Apr;26(4):1815-1825.

35

Sieren, M., Balks, M., Schlueter, J., Wegner, F., Hüllebrand, M., Scharfschwerdt, M., Barkhausen, J., Frydrychowicz, A., Gabbert, D., Oechtering,T.Comprehensive analysis of haemodynamics in patients with physiologically curved prostheses of the ascending aorta. Eur J Cardiothorac Surg.2022 Jun 15;62(1):ezab352.

34

Hennemuth, A., Hüllebrand, M., Doeblin, P., Krüger, N., Kelle, S.Anwendungen von künstlicher Intelligenz in der diagnostischen kardialen Bildanalyse.Der Kardiologe. 16, pages72–81 (2022)

33

Kramer, P., Schleiger, A., Schafstedde, M., Danne, F., Nordmeyer, J., Berger, F., Ovroutski, S. A Multimodal Score Accurately Classifies Fontan Failure and Late Mortality in Adult Fontan Patients. Front Cardiovasc Med. 2022 Mar 10;9:767503.

32

Escher, A., Strauch, C., Hubmann, E., Hübler, M., Bortis, D., Thamsen, B., Mueller, M., Kertzscher, U., Thamsen, P., Kolar, J., Zimpfer, D., Granegger, M.A Cavopulmonary Assist Device for Long-Term Therapy of Fontan Patients. Semin Thorac Cardiovasc Surg.2022 Spring;34(1):238-248.

31

Froese V, Gabel G, Parnell J, Prause A, Lommel M, Kertzscher U. Flow study on a transparent two-phase blood model fluid based on alginate microspheres.Exp Fluids 63, 188 (2022).

30

Petter E, Scheibenbogen C, Linz P, Stehning C, Wirth K, Kuehne T, Kelm M. Muscle sodium content in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. J Transl Med. 2022 Dec 9;20(1):580.

29

Brüning J, Kramer P, Goubergrits L, Schulz A, Murin P, Solowjowa N, Kuehne T, Berger F, Photiadis J, Weixler VH. 3D modeling and printing for complex biventricular repair of double outlet right ventricle. Front Cardiovasc Med. 2022 Nov 30;9:1024053

28

Al-Wakeel-Marquard N, Ferreira da Silva T, Berger F, Kuehne T, Messroghli DR. Myocardial extracellular volume is a non-invasive tissue marker of heart failure in patients with transposition of the great arteries and systemic right ventricle. Front Pediatr. 2022 Nov 7;10:949078.

27

Hellmeier F, Brüning J, Berg P, Saalfeld S, Spuler A, Sandalcioglu IE, Beuing O, Larsen N, Schaller J, Goubergrits L. Geometric uncertainty in intracranial aneurysm rupture status discrimination: a two-site retrospective study. BMJ Open. 2022 Nov 8;12(11):e063051.

26

Schafstedde M, Nordmeyer J, Berger F, Knosalla C, Mertins P, Regitz-Zagrosek V, Kuehne T, Kraus M, Nordmeyer S. Serum dihydrotestosterone is associated with adverse myocardial remodeling in patients with Aortic Valve Stenosis before and after Aortic Valve Replacement. Am J Physiol Heart Circ Physiol. 2022 Nov 1;323(5):H949-H957.

25

Geus PF, Hehnen F, Krakowski S, Lücke K, Hoon DSB, Frost N, Kertzscher U, Wendt G. Verification of a Novel Minimally Invasive Device for the Isolation of Rare Circulating Tumor Cells (CTC) in Cancer Patients’ Blood. Cancers (Basel). 2022 Sep 29; 14(19):4753.

24

Esslinger I, Schulz I, Bierewirtz T, Lommel M, Kertzscher U. Visualization of platelet deposition in a flow chamber: Investigation of different inorganic hard material coatings on titanium. Current Directions in Biomedical Engineering. 2022;8(2): 145-148.

23

Doeblin P, Jahnke C, Schneider M, Al-Tabatabaee S, Goetze C, Weiss KJ, Tanacli R, Faragli A, Witt U, Stehning C, Seidel F, Elsanhoury A, Kuehne T, Tschöpe C, Pieske B, Kelle S. CMR findings after COVID-19 and after COVID-19-vaccination—same but different? Int J Cardiovasc Imaging. 2022 May 12;38(9):2057–71.

22

Escher A, Hubmann EJ, Karner B, Messner B, Laufer G, Kertzscher U, Zimpfer D, Granegger M. Linking Hydraulic Properties to Hemolytic Performance of Rotodynamic Blood Pumps. Adv. Theory Simul. 2022, 5, 2200117.

21

Berndt N, Hudert CA, Eckstein J, Loddenkemper C, Henning S, Bufler P, Meierhofer D, Sack I, Wiegand S, Wallach I, Holzhütter HG. Alterations of Central Liver Metabolism of Pediatric Patients with Non-Alcoholic Fatty Liver Disease. Int J Mol Sci. 2022 Sep 21;23(19):11072.

20

Vellguth K, Barbieri F, Reinthaler M, Kasner M, Landmesser U, Kuehne T, Hennemuth A, Walczak L, Goubergrits L. Effect of transcatheter edge-to-edge repair device position on diastolic hemodynamic parameters: An echocardiography-based simulation study. Front. Cardiovasc. Med. 2022 Aug 24;9:915074.

19

Schafstedde M, Yevtushenko P, Nordmeyer S, Kramer P, Schleiger A, Solowjowa N, Berger F, Photiadis J, Mykychak Y, Cho MY, Ovroutski S, Kuehne T, Brüning J. Virtual treatment planning in three patients with univentricular physiology using computational fluid dynamics - Pitfalls and strategies. Front Cardiovasc Med. 2022 Aug 3;9:898701.

18

Schons M, Pilgram L, Reese JP, Stecher M, Anton G, Appel KS, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, Brechtel M, Brinkmann F, Brünn C, Dhillon C, Fiessler C, Geisler R, Hamelmann E, Hansch S, Hanses F, Hanß S, Herold S, Heyder R, Hofmann AL, Hopff SM, Horn A, Jakob C, Jiru-Hillmann S, Keil T, Khodamoradi Y, Kohls M, Kraus M, Krefting D, Kunze S, Kurth F, Lieb W, Lippert LJ, Lorbeer R, Lorenz-Depiereux B, Maetzler C, Miljukov O, Nauck M, Pape D, Püntmann V, Reinke L, Römmele C, Rudolph S, Sass J, Schäfer C, Schaller J, Schattschneider M, Scheer C, Scherer M, Schmidt S, Schmidt J, Seibel K, Stahl D, Steinbeis F, Störk S, Tauchert M, Tebbe JJ, Thibeault C, Toepfner N, Ungethüm K, Vadasz I, Valentin H, Wiedmann S, Zoller T, Nagel E, Krawczak M, von Kalle C, Illig T, Schreiber S, Witzenrath M, Heuschmann P, Vehreschild JJ; NAPKON Research Group. The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics. Eur J Epidemiol. 2022 Jul 29:1–22.

17

Goubergrits L, Vellguth K, Obermeier L, Schlief A, Tautz L, Bruening J, Lamecker H, Szengel A, Nemchyna O, Knosalla C, Kuehne T, Solowjowa N. CT-Based Analysis of Left Ventricular Hemodynamics Using Statistical Shape Modeling and Computational Fluid Dynamics. Front Cardiovasc Med. 2022; 9:901902.

16

Schmidt N, Behrbohm H, Goubergrits L, Hildebrandt T, Brüning J. Comparison of rhinomanometric and computational fluid dynamic assessment of nasal resistance with respect to measurement accuracy. Int J Comput Assist Radiol Surg. 2022 Sep;17(9):1519-1529.

15

Obermeier L, Vellguth K, Schlief A, Tautz L, Bruening J, Knosalla C, Kuehne T, Solowjowa N, Goubergrits L. CT-Based Simulation of Left Ventricular Hemodynamics: A Pilot Study in Mitral Regurgitation and Left Ventricle Aneurysm Patients. Front Cardiovasc Med. 2022 Mar 22;9:828556.

14

Doeblin P, Steinbeis F, Scannell CM, Goetze C, Al-Tabatabaee S, Erley J, Faragli A, Pröpper F, Witzenrath M, Zoller T, Stehning C, Gerhardt H, Sánchez-González J, Alskaf E, Kuehne T, Pieske B, Tschöpe C, Chiribiri A, Kelle S. Brief Research Report: Quantitative Analysis of Potential Coronary Microvascular Disease in Suspected Long-COVID Syndrome. Front Cardiovasc Med. 2022 May 31;9:877416

13

Sündermann SH, Hennemuth A, Kempfert J. Virtual reality in cardiac interventions - New tools or new toys? J Card Surg. 2022 Aug;37(8):2466-2468.

12

Kossen T, Hirzel MA, Madai VI, Boenisch F, Hennemuth A, Hildebrand K, Pokutta S, Sharma K, Hilbert A, Sobesky J, Galinovic I, Khalil AA, Fiebach JB, Frey D. Toward Sharing Brain Images: Differentially Private TOF-MRA Images With Segmentation Labels Using Generative Adversarial Networks. Front Artif Intell. 2022 May 2;5:813842.

11

Lalande A, Chen Z, Pommier T, Decourselle T, Qayyum A, Salomon M, Ginhac D, Skandarani Y, Boucher A, Brahim K, de Bruijne M, Camarasa R, Correia TM, Feng X, Girum KB, Hennemuth A, Huellebrand M, Hussain R, Ivantsits M, Ma J, Meyer C, Sharma R, Shi J, Tsekos NV, Varela M, Wang X, Yang S, Zhang H, Zhang Y, Zhou Y, Zhuang X, Couturier R, Meriaudeau F. Deep learning methods for automatic evaluation of delayed enhancement-MRI. The results of the EMIDEC challenge. Med Image Anal. 2022 Jul;79:102428.

10

Bingel A, Messroghli D, Weimar A, Runte K, Salcher-Konrad M, Kelle S, Pieske B, Berger F, Kuehne T, Goubergrits L, Fuerstenau D, Kelm M. Hemodynamic Changes During Physiological and Pharmacological Stress Testing in Patients With Heart Failure: A Systematic Review and Meta-Analysis. Front Cardiovasc Med. 2022 Apr 19;9:718114.

9

Huellebrand M, Ivantsits M, Tautz L, Kelle S, Hennemuth A. A Collaborative Approach for the Development and Application of Machine Learning Solutions for CMR-Based Cardiac Disease Classification. Front Cardiovasc Med. 2022 Mar 10;9:829512.

8

Latus H, Stammermann J, Voges I, Waschulzik B, Gutberlet M, Diller GP, Schranz D, Ewert P, Beerbaum P, Kühne T, Sarikouch S; German Competence Network for Congenital Heart Defects Investigators. Impact of Right Ventricular Pressure Load After Repair of Tetralogy of Fallot. J Am Heart Assoc. 2022 Mar 18:e022694.

7

Maechler M, Rösner J, Wallach I, Geiger JRP, Spies C, Liotta A, Berndt N. Sevoflurane Effects on Neuronal Energy Metabolism Correlate with Activity States while Mitochondrial Function Remains Intact. Int J Mol Sci. 2022 Mar 11;23(6):3037.

6

Tautz L, Walczak L, Manini C, Hennemuth A, Hüllebrand M. 3D Right Ventricle Reconstruction from 2D U-Net Segmentation of Sparse Short-Axis and 4-Chamber Cardiac Cine MRI Views. In: Puyol Antón E. et al. (eds) Statistical Atlases and Computational Models of the Heart. Multi-Disease, Multi-View, and Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge. STACOM 2021. Lecture Notes in Computer Science, 2022; vol 13131. Springer, Cham.

5

Subramaniam P, Kossen T, Ritter K, Hennemuth A, Hildebrand K, Hilbert A, Sobesky J, Livne M, Galinovic I, Khalil AA, Fiebach JB, Frey D, Madai VI. Generating 3D TOF-MRA volumes and segmentation labels using generative adversarial networks. Med Image Anal. 2022;78:102396.

4

Markó L, Dörr A, Linz P, van den Meiracker AH, Garrelds IM, Kuehne T, Dechend R, Danser AHJ, Flörcken A, Müller DN. Effect of Sunitinib Treatment on Skin Sodium Accumulation in Patients With Renal Cancer: a Pilot Study. Hypertension. 2022 May;79(5):e103-e105.

3

Aldoj N, Biavati F, Dewey M, Hennemuth A, Asbach P, Sack I. Fully automated quantification of in vivo viscoelasticity of prostate zones using magnetic resonance elastography with Dense U‑net segmentation. Scientific Reports. 2022 Feb 7;12(1):2001.

2

Escher A, Gobel H, Nicolai M, Schloglhofer T, Hubmann EJ, Laufer G, Messner B, Kertzscher U, Zimpfer D, Granegger M. Hemolytic Footprint of Rotodynamic Blood Pumps. IEEE Trans Biomed Eng. 2022 Aug;69(8):2423-2432.

1

Krüger N, Meyer A, Tautz L, Hüllebrand M, Wamala I, Pullig M, Kofler M, Kempfert J, Sündermann S, Falk V, Hennemuth A. Cascaded neural network-based CT image processing for aortic root analysis. Int J Comput Assist Radiol Surg. 2022 Mar;17(3):507-519.

Veröffentlichungen 2021

52

Friedrich S, Groß S, König I, Engelhardt S, Bahls M, Heinz J, Huber C, Kaderali L, Kelm M, Leha A, Rühl J, Schaller J, Scherer C, Vollmer M, Seidler T, Friede T.Applications of artificial intelligence/machine learning approaches in cardiovascular medicine: a systematic review with recommendations. Eur Heart J Digit Health.2021 Jun 8;2(3):424-436.

51

Lauten A, Martinovic M, Kursawe L, Kikhney J, Affeld K, Kertzscher U, Falk V, Moter A. Bacterial biofilms in infective endocarditis: an in vitro model to investigate emerging technologies of antimicrobial cardiovascular device coatings. Clinical Research in Cardiology 2020 May 22;110:323-331.

50

KIPeriOP-Group, Englert, A., Bendz, P.,[Artificial intelligence-augmented perioperative clinical decision support, KIPeriOP].Anaesthesist.2021 Nov;70(11):962-963.

49

Schleiger A, Kramer P, Sallmon H, Jentsch N, Pileckaite M, Danne F, Schafstedde M, Müller HP, Müller T, Tacke F, Jara M, Stockmann M, Berger F, Ovroutski S. Morphologic Alterations Precede Functional Hepatic Impairment as Determined by 13C-Methacetin Liver Function Breath Test in Adult Fontan Patients. Front Cardiovasc Med. 2021 Dec 23;8:764009.

48

Englert A, Bendz P; KIPeriOP-Group. KI-augmentierte perioperative klinische Entscheidungsunterstützung, KIPeriOP [Artificial intelligence-augmented perioperative clinical decision support, KIPeriOP]. Anaesthesist. 2021 Nov;70(11):962-963. German.

47

Al-Wakeel-Marquard N, Seidel F, Künisch J, Kuehne T, Berger F, Messroghli DR, Klaassen S. Midwall fibrosis and cardiac mechanics: rigid body rotation is a novel marker of disease severity in pediatric primary dilated cardiomyopathy. Front. Cardiovasc. Med. 2022 Feb 17;8:810005.

46

Walczak L, Tautz L, Neugebauer M, Georgii J, Wamala I, Sündermann S, Falk V, Hennemuth A. Interactive editing of virtual chordae tendineae for the simulation of the mitral valve in a decision support system. Int J Comput Assist Radiol Surg. 2021 Jan;16(1):125-132.

45

Geus P, Laidig D, Borchers P, Seel T, Stettin J, Kertzscher U. In vitro validation of a non-invasive continuous blood pressure measurement method for the perioperative application. Current Directions in Biomedical Engineering. 2021;7(2): 859-862.

44

Tanacli R, Doeblin P, Götze C, Zieschang V, Faragli A, Stehning C, Korosoglou G, Erley J, Weiss J, Berger A, Pröpper F, Steinbeis F, Kuehne T, Seidel F, Geisel D, Cannon Walter-Rittel T, Stawowy P, Witzenrath M, Klingel K, Van Linthout S, Pieske B, Tschöpe C, Kelle S . COVID-19 vs. Classical Myocarditis Associated Myocardial Injury Evaluated by Cardiac Magnetic Resonance and Endomyocardial Biopsy. Front. Cardiovasc. Med. 2021 Dec 24;8:737257.

43

Walczak L, Georgii J, Tautz L, Neugebauer M, Wamala I, Sündermann S, Falk V, Hennemuth A. Using Position-Based Dynamics for Simulating Mitral Valve Closure and Repair Procedures. Computer Graphics Forum 2021 41: 270-287.

42

Strecker C, Krafft AJ, Kaufhold L, Hüllebrandt M, Treppner M, Ludwig U, Köber G, Hennemuth A, Hennig J, Harloff A. Carotid Geometry and Wall Shear Stress Independently Predict Increased Wall Thickness-A Longitudinal 3D MRI Study in High-Risk Patients. Front Cardiovasc Med. 2021 Oct 26;8:723860.

41

Keshi E, Tang P, Weinhart M, Everwien H, Moosburner S, Seiffert N, Lommel M, Kertzscher U, Globke B, Reutzel-Selke A, Strücker B, Pratschke J, Sauer IM, Haep N, Hillebrandt KH. Surface modification of decellularized bovine carotid arteries with human vascular cells significantly reduces their thrombogenicity. J Biol Eng. 2021 Nov 24;15(1):26.

40

Berndt N, Eckstein J, Wallach I, Nordmeyer S, Kelm M, Kirchner M, Goubergrits L, Schafstedde M, Hennemuth A, Kraus M, Grune T, Mertins P, Kuehne T, Holzhütter HG. CARDIOKIN1: Computational Assessment of Myocardial Metabolic Capability in Healthy Controls and Patients With Valve Diseases. Circulation. 2021 Dec 14;144(24):1926-1939.

39

Seidel F, Kuehne T, Kelle S, Doeblin P, Zieschang V, Tschoepe C, Al-Wakeel-Marquard N, Nordmeyer S. Cardiovascular magnetic resonance findings in non-hospitalized paediatric patients after recovery from COVID-19. ESC Heart Fail. 2021 Dec;8(6):5583-5588.

38

Franz J, Czechowicz K, Waechter-Stehle I, Hellmeier F, Razafindrazaka F, Kelm M, Kempfert J, Meyer A, Archer G, Weese J, Hose R, Kuehne T, Goubergrits L. An orifice shape-based reduced order model of patient-specific mitral valve regurgitation. Engineering Applications of Computational Fluid Mechanics 2021:15(1):1868-1884

37

Strauch C, Escher A, Wulff S, Kertzscher U, Zimpfer D, Thamsen PU, Granegger M. Validation of Numerically Predicted Shear Stress-dependent Dissipative Losses Within a Rotary Blood Pump. ASAIO J. 2021 Oct 1;67(10):1148-1158.

36

Yevtushenko P, Goubergrits L, Gundelwein L, Setio AAA, Ramm H, Lamecker H, Heimann T, Meyer A, Kuehne T, Schafstedde M. Deep learning based centerline-aggregated aortic hemodynamics: an efficient alternative to numerical modelling of hemodynamics. IEEE Journal of Biomedical and Health Informatics, accepted. 2021:26(4):1815-1825

35

Garczynska K, Tzschätzsch H, Assili S, Kühl AA, Häckel A, Schellenberger E, Berndt N, Holzhütter HG, Braun J, Sack I, Guo J. Effect of Post-mortem Interval and Perfusion on the Biophysical Properties of ex vivo Liver Tissue Investigated Longitudinally by MRE and DWI. Front. Physiol. 2021 Aug 3:12:696304.

34

Franke B, Bruehning J, Yevtushenko P, Dreger H, Brand A, Unbehaun A, Kempfert J, Sündermann S, Lemboke A, Solowjowa, Kelle S, Falk V, Kuehne T, Goubergrits L, Schafstedde M..Computed Tomography Based Assessment of Transvalvular Pressure Gradient in Aortic Stenosis. Frontiers in Cardiovascular Medicine.Front. Cardiovasc. Med. 2021 Sep 08:8: 706628.

33

Schafstedde M, Nordmeyer S, Schleiger A, Nordmeyer J, Berger F, Kramer P, Ovroutski S. Persisting and reoccurring cyanosis after Fontan operation is associated with increased late mortality.Eur Journal of Cardiothorac Surg. 2021 Jul 1:61(1):54-61.

32

Faragli A, Alogna A, Lee CB, Zhu M, Ghorbani N, Muzio FPL, Schnackenburg B, Stehning C, Kuehne T, Post H, Goubergrits L, Nagel E, Pieske B, Kelle S, Kelm M. .Non-invasive CMR-based quantification of myocardial power and efficiency under stress and ischemic conditions in Landrace pigs Myocardial efficiency during stress and ischemia.Frontiers in Cardiovascular Medicine; 2021 Jul;8:689255

31

Friedrich S, Groß G, König IR, Engelhardt S, Bahls M, Heinz J, Huber C, Kaderali L, Kelm K, Leha A, Rühl J, Schaller J, Scherer C, Vollmer M, Seidler T, Friede T. Applications of AI/ML approaches in cardiovascular medicine: A systematic review with recommendations. European Heart Journal - Digital Health. 2021 June;2(3):424-436.

30

Lommel M, Froese V, Sieber M, Jentzsch M, Bierewirtz T, Hasirci Ü, Rese T, Seefeldt J, Schimek S, Kertzscher U, Paschereit CO. Novel measurement system for respiratory aerosols and droplets in indoor environments. Wiley. 2021 June;31(6):1860-1873

29

Berndt N, Eckstein J, Heucke N, Wuensch T, Gajowski R, Stockmann M, Meierhofer D, Holzhütter HG. Metabolic heterogeneity of human hepatocellular carcinoma: implications for personalized pharmacological treatment. FEBS J. 2021 Apr;288(7):2332-2346.

28

Boraschi A, Bozzi S, Thamsen B, Granegger M, Wiegmann L, Pappalardo F, Slepian MJ, Kurtcuoglu V, Redaelli A, De Zélicourt D, Consolo F. Thrombotic Risk of Rotor Speed Modulation Regimes of Contemporary Centrifugal Continuous-flow Left Ventricular Assist Devices. ASAIO J. 2021 Jul 1;67(7):737-745.

27

Berndt N, Kolbe E, Gajowski R, Eckstein J, Ott F, Meierhofer D, Holzhütter HG, Matz-Soja M. Functional consequences of metabolic zonation in murine livers: New insights for an old story. Hepatology. 2021 Feb;73(2):795-810.

26

Puder L, Roth S, Krabusch P, Wiegand S, Opitz R, Bald M, Flück C, Schulz E, Voss E, Markó L, Linz P, Berger F, Müller DN, Kuehne T, Litt MJ, Cone RD, Kühnen P, Kelm M. Cardiac phenotype and tissue sodium content in adolescents with defects in the melanocortin system. J Clin Endocrinol Metab. 2021;106(9):2606-2616

25

Ivantsits M, Goubergrits L, Brüning J, Spuler A, Hennemuth A. (2021) Intracranial Aneurysm Rupture Prediction with Computational Fluid Dynamics Point Clouds. In: Hennemuth A, Goubergrits L, Ivantsits M, Kuhnigk JM. (eds) Cerebral Aneurysm Detection. CADA 2020. Lecture Notes in Computer Science, vol 12643. Springer, Cham.

24

Ivantsits M, Huellebrand M, Kelle S, Kuehne T, Hennemuth A. (2021) Intracranial Aneurysm Rupture Risk Estimation Utilizing Vessel-Graphs and Machine Learning. In: Hennemuth A, Goubergrits L, Ivantsits M, Kuhnigk JM. (eds) Cerebral Aneurysm Detection. CADA 2020. Lecture Notes in Computer Science, vol 12643. Springer, Cham.

23

Ivantsits M, Kuhnigk JM, Huellebrand M, Kuehne T, Hennemuth A. (2021) Deep Learning-Based 3D U-Net Cerebral Aneurysm Detection. In: Hennemuth A, Goubergrits L, Ivantsits M, Kuhnigk JM. (eds) Cerebral Aneurysm Detection. CADA 2020. Lecture Notes in Computer Science, vol 12643. Springer, Cham.

22

Spuler A, Goubergrits L. CADA: Clinical Background and Motivation. In: Hennemuth A, Goubergrits L, Ivantsits M, Kuhnigk JM. (eds) Cerebral Aneurysm Detection. CADA 2020. Lecture Notes in Computer Science, vol 12643. Springer, Cham.

21

Ivantsits M, Goubergrits L, Kuhnigk JM, Huellebrand M, Brüning J, Kossen T, Pfahringer B, Schaller J, Spuler A, Kuehne T, Hennemuth A. (2021) Cerebral Aneurysm Detection and Analysis Challenge 2020 (CADA). In: Hennemuth A., Goubergrits L., Ivantsits M., Kuhnigk JM. (eds) Cerebral Aneurysm Detection. CADA 2020. Lecture Notes in Computer Science, vol 12643. Springer, Cham.

20

Berndt N, Kovács R, Schoknecht K, Rösner J, Reiffurth C, Maechler M, Holzhütter HG, Dreier JP, Spies C, Liotta A. Low neuronal metabolism during isoflurane-induced burst suppression is related to synaptic inhibition while neurovascular coupling and mitochondrial function remain intact. JCBFM. 2021 Oct;41(10):2640-2655.

19

Schreyer S, Berndt N, Eckstein J, Mülleder M, Hemmati-Sadeghi S, Klein C, Abuelnor B, Panzel A, Meierhofer D, Spranger J, Steiner B, Brachs S. Dietary-challenged mice with Alzheimer-like pathology show increased energy expenditure and reduced adipocyte hypertrophy and steatosis. Aging (Albany NY). 2021 Apr 16;13(8):10891-10919.

18

Unbehaun A, Kelm M, Miera O, Kempfert J. Transcatheter aortic valve implantation in a 13-year-old child with end-stage heart failure: a case report. Eur Heart J Case Rep. 2021 Feb 16;5(2):ytab034.

17

Berndt N, Holzhütter HG. Computational Hypothesis: How Intra-Hepatic Functional Heterogeneity May Influence the Cascading Progression of Free Fatty Acid-Induced Non-Alcoholic Fatty Liver Disease (NAFLD). Cells. 2021; 10(3):578.

16

Rank N, Stoiber L, Nasser M, Tanacli R, Stehning C, Knierim J, Schoenrath F, Pieske B, Falk V, Kuehne T, Meyer A, Kelle S. Assessment of 10-Year Left-Ventricular-Remodeling by CMR in Patients Following Aortic Valve Replacement. Front Cardiovasc Med. 2021; 8:645693.

15

Huellebrand M, Ivantsits M, Zhang H, Kohlmann P, Kuhnigk JM, Kuehne T, Schönberg S, Hennemuth A. Comparison of a Hybrid Mixture Model and a CNN for the Segmentation of Myocardial Pathologies in Delayed Enhancement MRI. In: Puyol Anton E. et al. (eds) Statistical Atlases and Computational Models of the Heart. M&Ms and EMIDEC Challenges. STACOM 2020. Lecture Notes in Computer Science, 2021; vol 12592. Springer, Cham.

14

Ivantsits M, Huellebrand M, Kelle S, Schönberg SO, Kuehne T, Hennemuth A. Deep-Learning-Based Myocardial Pathology Detection. In: Puyol Anton E. et al. (eds) Statistical Atlases and Computational Models of the Heart. M&Ms and EMIDEC Challenges. STACOM 2020. Lecture Notes in Computer Science,2021; vol 12592. Springer, Cham.

13

Al-Wakeel-Marquard N, Seidel F, Herbst C, Kühnisch J, Kuehne T, Berger F, Klaassen S, Messroghli DR. Diffuse myocardial fibrosis by T1 mapping is associated with heart failure in pediatric primary dilated cardiomyopathy. Int J Cardiol. 2021 Jun 15;333:219-225.

12

Schleiger A, Kramer P, Schafstedde M, Yigitbasi M, Danne F, Murin P, Cho MY, Photiadis J, Berger F, Ovroutski S. Can Left Atrioventricular Valve Reduction Index (LAVRI) Predict the Surgical Strategy for Repair of Atrioventricular Septal Defect? Pediatr Cardiol. 2021 Apr;42(4):898-905.

11

Lauten A, Martinović M, Kursawe L, Kikhney J, Affeld K, Kertzscher U, Falk V, Moter A. Bacterial biofilms in infective endocarditis: an in vitro model to investigate emerging technologies of antimicrobial cardiovascular device coatings. Clin Res Cardiol. 2021 Mar;110(3):323-331.

10

Nordmeyer S, Lee CB, Goubergrits L, Knosalla C, Berger F, Falk V, Ghorbani N, Hireche-Chikaoui H, Zhu M, Kelle S, Kuehne T, Kelm M. Circulatory efficiency in patients with severe aortic valve stenosis before and after aortic valve replacement. J Cardiovasc Magn Reson. 2021 Mar 1;23(1):15.

9

Kossen T, Subramaniam P, Madai VI, Hennemuth A, Hildebrand K, Hilbert A, Sobesky J, Livne M, Galinovic I, Khalil AA, Fiebach JB, Frey D. Synthesizing anonymized and labeled TOF-MRA patches for brain vessel segmentation using generative adversarial networks. Comput Biol Med. 2021 Feb 15;131:104254.

8

Moscato F, Gross C, Maw M, Schlöglhofer T, Granegger M, Zimpfer D, Schima H. The left ventricular assist device as a patient monitoring system. Ann Cardiothorac Surg. 2021 Mar;10(2):221-232.

7

Thamsen B, Yevtushenko P, Gundelwein L, Setio AAA, Lamecker H, Kelm M, Schafstedde M, Heimann T, Kuehne T, Goubergrits L. Synthetic Database of Aortic Morphometry and Hemodynamics: Overcoming Medical Imaging Data Availability. IEEE Trans Med Imaging. 2021 May;40(5):1438-1449.

6

Ferrari A, Giampietro C, Bachmann B, Bernardi L, Bezuidenhhout D, Ermanni P, Hopf R, Kitz S, Kress G, Loosli C, Marina V, Meboldt M, Pellegrini G, Poulikakos D, Rebholz M, Schmid Daners M, Schmidt T, Starck C, Stefopoulos G, Sündermann S, Thamsen B, Zilla P, Potapov E, Falk V, Mazza E. A Novel Hybrid Membrane VAD as First Step Toward Hemocompatible Blood Propulsion. Ann Biomed Eng. 2021 Feb;49(2):716-731.

5

Hashemi D, Motzkus L, Blum M, Kraft R, Tanacli R, Tahirovic E, Doeblin P, Zieschang V, Zamani SM, Kelm M, Kuehne T, Pieske B, Alogna A, Edelmann F, Duengen HD, Kelle S. Myocardial deformation assessed among heart failure entities by cardiovascular magnetic resonance imaging. ESC Heart Fail. 2021 April;8(2):890-897.

4

Al-Wakeel-Marquard N, Ferreira da Silva T, Jeuthe S, Rastin S, Muench F, O H-Ici D, Yilmaz S, Berger F, Kuehne T, Messroghli DR. Measuring myocardial extracellular volume of the right ventricle in patients with congenital heart disease. Sci Rep. 2021 Jan 29;11(1):2679. doi: 10.1038/s41598-021-81440-z. PMID: 33514806.

3

Runte K, Brosien K, Schubert C, Nordmeyer J, Kramer P, Schubert S, Berger F, Hennemuth A, Kuehne T, Kelm M, Goubergrits L..Image-based computational model predicts dobutamine-induced hemodynamic changes in patients with aortic coarctation. Circ: Cardiovascular Imaging. 2021 Feb;14(2):e011523

2

Tschöpe C, Sherif M, Anker MS, Geisel D, Kuehne T, Kelle S. COVID-19-convalescence phase unmasks a silent myocardial infarction due to coronary plaque rupture. ESC Heart Fail. 2021 Jan 6.

1

Granegger M, Küng S, Bollhalder O, Quandt D, Scheifele C, Drozdov D, Held U, Callegari A, Kretschmar O, Hübler M, Schweiger M, Knirsch W. Serial assessment of somatic and cardiovascular development in patients with single ventricle undergoing Fontan procedure. Int J Cardiol. 2021 Jan 1;322:135-141.

Veröffentlichungen 2020

44

Huellebrand M, Messroghli D, Tautz L, Kuehne T, Hennemuth A. An extensible software platform for interdisciplinary cardiovascular imaging research. Comput Methods Programs Biomed. 2020 Feb;184:105277.

43

Granegger M, Thamsen B, Schlöglhofer T, Lach S, Escher A, Haas T, Meboldt M, Schweiger M, Hübler M, Zimpfer D. Blood trauma potential of the HeartWare Ventricular Assist Device in pediatric patients. J Thorac Cardiovasc Surg. 2020 Apr;159(4):1519-1527.e1.

42

Sieren, M., Schultz, V., Fujita, B., Wegner, F., Hüllebrand, M., Scharfschwerdt, M., Sievers, H., Barkhausen, J., Frydrychowicz, A., Oechtering, T.4D flow CMR analysis comparing patients with anatomically shaped aortic sinus prostheses, tube prostheses and healthy subjects introducing the wall shear stress gradient: a case control studyJ Cardiovasc Magn Reson.2020 Aug 10;22(1):59.

41

Mühlbacher, J., Pröbstl, C., Granegger, M., Schiefer, J., Duma, A., Hüpfl, M., Herkner, H., Röhrich, M.,Schebesta, K.Impact of Infant Positioning on Cardiopulmonary Resuscitation Performance During Simulated Pediatric Cardiac Arrest: A Randomized Crossover Study. Pediatr Crit Care Med.2020 Dec;21(12):e1076-e1083.

40

Degener, F., Salameh, A., Manuylova, T., Pickardt, T., Kostelka, M., Daehnert, I., Berger, F., Messroghli, D., Schubert, S., Klingel, K.First paediatric cohort for the evaluation of inflammation in endomyocardial biopsies derived from congenital heart surgery. Int J Cardiol.2020 Mar 15;303:36-40.

39

Poller, W., Haas, J., Klingel, K., Kühnisch, J., Gast, M., Kaya, Z., Escher, F., Kayvanpour, E., Degener, F., Opgen-Rhein, B., Berger, F., Mochmann, H., Skurk, C., Heidecker, B., Schultheiss, H., Monserrat, L., Meder, B., Landmesser, U., Klaassen, S.Familial Recurrent Myocarditis Triggered by Exercise in Patients With a Truncating Variant of the Desmoplakin Gene .J Am Heart Assoc.2020 May 18;9(10):e015289.

38

Granegger, M., Thamsen, B., Schlöglhofer, T., Lach, S., Escher, A., Haas, T., Meboldt, M., Schweiger, M., Hübler, M., Zimpfer, D.Blood trauma potential of the HeartWare Ventricular Assist Device in pediatric patients. J Thorac Cardiovasc Surg.2020 Apr;159(4):1519-1527.e1

37

Thamsen, B., Gülan, U., Wiegmann, L., Loosli, C., Schmid Daners, M., Kurtcuoglu, V., Holzner, M., Meboldt, M.Assessment of the Flow Field in the HeartMate 3 Using Three-Dimensional Particle Tracking Velocimetry and Comparison to Computational Fluid Dynamics. ASAIO J.2020 Feb;66(2):173-182.

36

Hüllebrand, M., Messroghli, D., Tautz, L. Kuehne,T., Hennemuth, A.An extensible software platform for interdisciplinary cardiovascular imaging researchComput Methods Programs Biomed.2020 Feb;184:105277.

35

Nordmeyer S, Krettek S, Nordmeyer J, Schafstedde M, Rehm K, Photiadis J, Berger F, Ovroutski S. Fontan completion during winter season is not associated with higher mortality or morbidity in the early postoperative period. Cardiol Young. 2020;30(5):629-632.

34

Rank N, Pfahringer B, Kempfert J, Stamm C., Kuehne T, Schoenrath F, Falk V, Eickhoff C, Meyer A. Deep-learning-based real-time prediction of acute kidney injury outperforms human predictive performance. NPJ Digit Med. 2020 Oct 26;3:139.

33

Hellmeier F, Bruening J, Sündermann S, Jarmatz L, Schafstedde M, Goubergrits L, Kuehne T, Nordmeyer S.Hemodynamic Modelling of biological aortic valve replacement using preoperative data only.Frontiers in Cardiovascular Medicine. 2021 Feb 9;7:593709.

32

Stiehm M, Brandt-Wunderlich C, Siewert S, Schmitz K, Grabow N, Goubergrits L, Kühne T, Poon EKW, Ooi A, Barlis P. Sensitivity analysis of FDA´s benchmark nozzle regarding in vitro imperfections - Do we need asymmetric CFD benchmarks? Current Directions in Biomedical Engineering 2020;6(3):78-81.

31

Berndt N, Egners A, Mastrobuoni G, Vvedenskaya O, Fragoulis A, Dugourd A, Bulik S, Pietzke M, Bielow C, van Gassel R, Damink SWO, Erdem M, Saez-Rodriguez J, Holzhütter HG, Kempa S, Cramer T. Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer. Br J Cancer. 2020;122(2):233-244.

30

Garczyńska K, Tzschätzsch H, Kühl AA, Morr AS, Lilaj L, Häckel A, Schellenberger E, Berndt N, Holzhütter HG, Braun J, Sack I, Guo J. Changes in Liver Mechanical Properties and Water Diffusivity During Normal Pregnancy Are Driven by Cellular Hypertrophy. Front Physiol. 2020 Nov 23;11:605205.

29

Schubert C, Brüning J, Goubergrits L, Hennemuth A, Berger F, Kuehne T, Kelm M. Assessment of hemodynamic responses to exercise in aortic coarctation using MRI-ergometry in combination with computational fluid dynamics. Scientific reports 2020;10:18894.

28

Ivantsits M, Tautz L, Sündermann S, Wamala I, Kempfert J, Kuehne T, Falk V, Hennemuth A. DL-based segmentation of endoscopic scenes for mitral valve repair. Current Directions in Biomedical Engineering 2020;6(1):20200017.

27

Tautz L, Zhang H, Hüllebrand M, Ivantsits M, Kelle S, Kuehne T, Falk V, Hennemuth A. Cardiac radiomics: an interactive approach for 4D data exploration. Current Directions in Biomedical Engineering 2020;6(1):20200008.

26

Vellguth K, Sündermann S, Escher A, Bierewirtz T, Schmidt T, Alogna A, Kertzscher U, Goubergrits L, Fraser KH, Granegger M. Intraventricular flow features and cardiac mechano-energetics after mitral valve interventions – feasibility of an isolated heart model. Current Directions in Biomedical Engineering 2020;6(1):20200028.

25

Walczak L, Goubergrits L, Hüllebrand M, Georgii J, Falk V, Hennemuth A. Using position-based dynamics to simulate deformation in aortic valve replacement procedure. Current Directions in Biomedical Engineering 2020;6(1):20200042.

24

Hanik M, Hege HC, Hennemuth A, von Tycowicz C. Nonlinear Regression on Manifolds for Shape Analysis using Intrinsic Bézier Splines. MICCAI 2020;12264:Springer, Cham.

23

Thamsen B, Yevtushenko P, Gundelweein L, Lamecker H, Kuehne T, Goubergrits L. Unsupervised Learning and Statistical Shape Modeling of the Morphometry and Hemodynamics of Coarctation of the Aorta. MICCAI 2020;12264:Springer, Cham.

22

Stegbauer J, Kraus M, Nordmeyer S, Kirchner M, Ziehm M, Dommisch H, Kelle S, Kelm M, Baczkó I, Landmesser U, Tschöpe C, Knosalla C, Falcke M, Schapranow MP, Regitz-Zagrosek V, Mertins P, Kühne T. Proteomic analysis reveals upregulation of ACE2, the putative SARS-CoV-2 receptor in pressure- but not volume-overloaded human hearts. Hypertension 2020;76:e41–e43.

21

Strecker C, Krafft AJ, Kaufhold L, Hüllebrandt M, Weber S, Ludwig U, Wolkewitz M, Hennemuth A, Hennig J, Harloff A. Carotid geometry is an independent predictor of wall thickness – a 3D cardiovascular magnetic resonance study in patients with high cardiovascular risk. Journal of Cardiovascular Magnetic Resonance 2020;22:67.

20

Kulka MW, Smatty S, Hehnen F, Bierewirtz T, Silberreis K, Nie C, Kerkhoff Y, Grötzinger C, Friedrich S, Dahms LI, Dernedde J, Grunwald I, Schirner M, Kertzscher U, Affeld K, Haag R. The Application of Dual-Layer, Mussel-Inspired, Antifouling Polyglycerol-Based Coatings in Ventricular Assist Devices. Advanced Materials Interfaces 2020 Sep 06;7(21):p.2000272.

19

Stoiber L, Ghorbani N, Kelm M, Kuehne T, Rank N, Lapinskas T, Stehning C, Pieske B, Falk V, Gebker R, Kelle S. Validation of simple measures of aortic distensibility based on standard 4‑chamber cine CMR: a new approach for clinical studies. Clinical Reaserch in Cardiology 2020;109:454-464.

18

Schubert C, Archer G, Zelis JM, Nordmeyer S, Runte K, Hennemuth A, Berger F, Falk V, Tonino PAL, Hose R, Horst H, Kuehne T, Kelm M. Wearable devices can predict the outcome of standardized 6-minute walk tests in heart disease. Nature Digital Medicine 2020;3:92.

17

Kuehne T, Meyer A, Hennemuth A. Digitale Transformation: Dies ist erst der Anfang ... Dtsch Arztebl 2020;117(15):28.

16

Oechtering TH, Sieren M, Hunold P, Hennemuth A, Huellebrand M, Scharfschwerdt M, Richardt D, Sievers H-H, Barkhausen J, Frydrychowicz A. Time-resolved 3-dimensional magnetic resonance phase contrast imaging (4D Flow MRI) reveals altered blood flow patterns in the ascending aorta of patients with valve-sparing aortic root replacement. Journal of Thoracic and Cardiovascular Surgery 2020;159(3):798-810.e1.

15

Blum M, Hashemi D, Motzkus LA, Neye M, Dordevic A, Zieschang V, Zamani SM, Lapinskas T, Runte K, Kelm M, Kuehne T, Tahirovic E, Edelmann F, Pieske B, Düngen H-D, Kelle S. Variability of Myocardial Strain During Isometric Exercise in Subjects With and Without Heart Failure. Frontiers in Cardiovascular Medicine 2020 Jun 30;7:111.

14

Berndt N, Kovács R, Rösner J, Wallach I, Dreier JP, Liotta A. Flavin Adenine Dinucleotide Fluorescence as an Early Marker of Mitochondrial Impairment During Brain Hypoxia. Int. J. Mol. Sci. 2020 Jun 1;21(11):3977.

13

Franke B, Weese J, Waechter-Stehle I, Brüning J, Kühne T, Goubergrits L. Towards improving the accuracy of Aortic Transvalvular Pressure Gradients: Rethinking Bernoulli. Medical & Biological Engineering & Computing 2020 May 26;58:1667-1679.

12

Marx L, Gsell MAF, Rund A, Caforio F, Prassl AJ, Toth-Gayor G, Kuehne T, Augustin CM, Plank G. Personalization of Electro-Mechanical Models of the Pressure-Overloaded Left Ventricle: Fitting of Windkessel-type Afterload Models. Philos. Trans. R. Soc. A 2020;378(2173):20190342.

11

Chitiboi T, Kanski M, Tautz L, Hennemuth A, Halpern D, Sherrid M, Axel L. Analysis of three‑chamber view conventional and tagged cine MRI in patients with suspected hypertrophic cardiomyopathy. MAGMA 2020 May 09;33:613-626.

10

Escher A, Choi Y, Callaghan F, Thamsen B, Kertzscher U, Schweiger M, Hübler M, Granegger M. A Valveless Pulsatile Pump for Heart Failure with Preserved Ejection Fraction: Hemo- and Fluid Dynamic Feasibility. Ann Biomed Eng 2020;48:1821-1836.

9

Ghorbani N, Muthurangu V, Khushnood A, Goubergrits L, Nordmeyer S, Fernandes JF, Lee C-B, Runte K, Roth S, Schubert S, Kelle S, Berger F, Kuehne T, Kelm M. Impact of Valve Morphology, Hypertension and Age on Aortic Wall Properties in Patients with Coarctation: a two-centre cross-sectional study. BMJ Open 2020;10:e03485.

8

Kespohl M, Bredow C, Klingel K, Voß M, Paeschke A, Zickler M, Poller W, Kaya Z, Eckstein J, Fechner H, Spranger J, Fähling M, Wirth EK, Radoshevich L, Thery F, Impens F, Berndt N, Knobeloch K-P, Beling A. Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming. Sci Adv. 2020 Mar 11;6(11):eaay1109.

7

Brüning J, Hildebrandt T, Heppt W, Schmidt N, Lamecker H, Szengel A, Amiridze N, Ramm H, Bindernagel M, Zachow S, Goubergrits L. Characterization of the Airflow within an Average Geometry of the Healthy Human Nasal Cavity. Sci Rep 2020;10:3755.

6

Holzhütter HG, Wuensch T, Gajowski R, Berndt N, Bulik S, Meierhofer D, Stockmann M. A novel variant of the 13C‑methacetin liver function breath test that eliminates the confounding effect of individual differencesin systemic CO2 kinetics. Arch Toxicol. 2020 Feb;94(2):401-415.

5

Kranzusch R, aus dem Siepen F, Wiesemann S, Zange L, Jeuthe S, Ferreira da Silva T, Kuehne T, Pieske B, Tillmanns C, Friedrich MG, Schulz-Menger J, Messroghli DR. Z-score mapping for standardized analysis and reporting of cardiovascular magnetic resonance modified Look-Locker inversion recovery (MOLLI) T1 data: Normal behavior and validation in patients with amyloidosis. J Cardiovasc Magn Reson 2020;20;22(1):6.

4

Aigner P, Schweiger M, Fraser K, Choi Y, Lemme F, Cesarovic N, Kertzscher U, Schima H, Hübler M, Granegger M. Ventricular Flow Field Visualization During Mechanical Circulatory Support in the Assisted Isolated Beating Heart. J Magn Reson Imaging 2020;48:794-804.

3

Tautz L, Walczak L, Georg J, Jazaerli A, Vellguth K, Wamala I, Sündermann S, Falk V, Hennemuth A. Combining position-based dynamics and gradient vector flow for 4D mitral valve segmentation in TEE sequences. IJCARS 2020;15:119-128.

2

Schuchardt FF, Kaller CP, Strecker C, Lambeck J, Wehrum T, Hennemuth A, Anastasopoulos C, Mader I, Harloff A. Hemodynamics of cerebral veins analyzed by 2d and 4d flow MRI and ultrasound in healthy volunteers and patients with multiple sclerosis. J Magn Reson Imaging 2020;51:205-217.

1

Nordmeyer S, Hellmeier F, Yevtushenko P, Kelm M, Lee C-B, Lehmann D, Kropf S, Berger F, Falk V, Knosalla C, Kuehne T, Goubergrits L. Abnormal aortic flow profiles persist after aortic valve replacement in the majority of patients with aortic valve disease - How model based personalized therapy planning could improve results - a pilot study approach. European Journal of Cardio-Thoracic Surgery 2020 Jan;57:133-141.

Veröffentlichungen 2019

49

Schubert, S., Opgen-Rhein, B., Boehne, M., Weigelt, A., Wagner, R., Müller, G., Rentzsch, A., Zu Knyphausen, E., Fischer, M., Papakostas, K., Wiegand, G., Ruf, B., Hannes, T., Reineker, K., Kiski, D., Khalil, M., Steinmetz, M., Fischer, G., Pickardt, T., Klingel, K., Messroghli, D., Degener, F., MYKKE consortium.Severe heart failure and the need for mechanical circulatory support and heart transplantation in pediatric patients with myocarditis: Results from the prospective multicenter registry "MYKKE". Pediatr Transplant;2019 Nov;23(7):e13548.

48

Krafft A., Licht, C., Kaufhold, L., Strecker, C., Huellebrand, M., Hennig, J., Harloff, A., Hennemuth, A., Ludwig, U.Quantitative Multi-contrast Vessel Wall Imaging in the Carotid Arteries: Preliminary Results on Reproducibility in Healthy Volunteers.2100

47

Zimmermann, J., Tautz, L., Meierhofer, C., Stern, H., Menze, B., Hennemuth, A.Fully dimensional vessel segmentation in non-contrast-enhanced 3D PC-MRI image data.1966

46

Schubert, S., Kelm, M., Koneti, N., Berger, F.First European experience of percutaneous closure of ventricular septal defects using a new CE-marked VSD occluder.2019 Jun 12;15(3):e242-e243.

45

Lommel,M., Goubergrits, L., Affeld, K., Kertzscher, U.Couette shearing device for the investigation of shear-induced damage of the primary hemostasis by left ventricular assist devices.Epub 2018 Oct 22.;2019 Jun 12;15(3):e242-e243.

44

Zimmermann, J., Drexl, J., Nordmeyer, S., Hennemuth, A.Computational metrics for quantitative characterization of vortical flow patterns based on 3D PC-MRI data.Proc. Intl. Soc. Mag. Reson. Med. 27 (2019).

43

Hennemuth, A., Kuhnigk, J., Steinmetz, M., Kelle, S., Chitiboi, T., Frahm,J., Huellebrand, M. Automatic Analysis of Multicycle Real-time MRI for the Assessment of Variable Cardiac Function based on Multi-orientation U-net Segmentation.Cardiac MRI, 2019 Feb.;2127.

42

Walczak, L., Georgii, J., Tautz, L., Neugebauer, M., Wamala, I., Sündermann, S., Falk, V. and Hennemuth, A. Using Position-Based Dynamics for Simulating Mitral Valve Closure and Repair Procedures. Computer Graphics Forum, 41: 270-287.

41

Zhong L, Schrauben EM, Garcia J, Uribe S, Grieve SM, Elbaz MSM, Barker AJ, Geiger J, Nordmeyer S, Marsden A, Carlsson M, Tan RS, Garg P, Westenberg JJM, Markl M, Ebbers T. Intracardiac 4D Flow MRI in Congenital Heart Disease: Recommendations on Behalf of the ISMRM Flow & Motion Study Group. J Magn Reson Imaging. 2019 Sep;50(3):677-681.

40

Nordmeyer S, Kretzschmar J, Murin P, Cho MY, Foth R, Schlichting U, Berger F, Ovroutski S, Photiadis J, Sigler M. ADAPT-treated pericardium for aortic valve reconstruction in congenital heart disease: histological analysis of a series of human explants. Eur J Cardiothorac Surg. 2019 Dec 1;56(6):1170-1177.

39

Kühnisch J, Herbst C, Al-Wakeel-Marquard N, Dartsch J, Holtgrewe M, Baban A, Mearini G, Hardt J, Kolokotronis K, Gerull B, Carrier L, Beule D, Schubert S, Messroghli D, Degener F, Berger F, Klaassen S. Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3. Clin Genet. 2019 Dec;96(6):549-559.

38

Granegger M, Valencia A, Quandt D, Dave H, Kretschmar O, Hübler M, Schweiger M. Approaches to Establish Extracardiac Total Cavopulmonary Connections in Animal Models-A Review. World J Pediatr Congenit Heart Surg. 2019 Jan;10(1):81-89.

37

Salehi Ravesh M, Langguth P, Pfarr JA, Schupp J, Trentmann J, Koktzoglou I, Edelman RR, Graessner J, Greiser A, Hautemann D, Hennemuth A, Both M, Jansen O, Hövener JB, Schäfer JP. Non-contrast-enhanced magnetic resonance imaging for visualization and quantification of endovascular aortic prosthesis, their endoleaks and aneurysm sacs at 1.5 T. Magn Reson Imaging. 2019 Jul;60:164-172.

36

Kelm M, Goubergrits L, Bruening J, Yevtushenko P, Fernandes JF, Sündermann SH, Berger F, Falk V, Kuehne T, Nordmeyer S; CARDIOPROOF group. Publisher Correction: Model-Based Therapy Planning Allows Prediction of Haemodynamic Outcome after Aortic Valve Replacement. Sci Rep. 2019 Feb 26;9(1):3327.

35

Wiegmann L, Thamsen B, de Zélicourt D, Granegger M, Boës S, Schmid Daners M, Meboldt M, Kurtcuoglu V. Fluid Dynamics in the HeartMate 3: Influence of the Artificial Pulse Feature and Residual Cardiac Pulsation. Artif Organs. 2019 Apr;43(4):363-376.

34

Boes S, Thamsen B, Haas M, Daners MS, Meboldt M, Granegger M. Hydraulic Characterization of Implantable Rotary Blood Pumps. IEEE Trans Biomed Eng. 2019 Jun;66(6):1618-1627.

33

Granegger M, Valencia A, Quandt D, Dave H, Kretschmar O, Hübler M, Schweiger M. Approaches to Establish Extracardiac Total Cavopulmonary Connections in Animal Models-A Review. World J Pediatr Congenit Heart Surg. 2019 Jan;10(1):81-89.

32

Granegger M, Dave H, Knirsch W, Thamsen B, Schweiger M, Hübler M. A Valveless Pulsatile Pump for the Treatment of Heart Failure with Preserved Ejection Fraction: A Simulation Study. Cardiovasc Eng Technol. 2019 Mar;10(1):69-79.

31

Petrou A, Granegger M, Meboldt M, Schmid Daners M. A Versatile Hybrid Mock Circulation for Hydraulic Investigations of Active and Passive Cardiovascular Implants. ASAIO J. 2019 Jul;65(5):495-502.

30

Granegger M, Choi Y, Locher B, Aigner P, Hubmann EJ, Lemme F, Cesarovic N, Hübler M, Schweiger M. Comparative analysis of cardiac mechano-energetics in isolated hearts supported by pulsatile or rotary blood pumps. Sci Rep. 2019 Dec 27;9(1):20058.

29

Roth S, Markó L, Birukov A, Hennemuth A, Kühnen P, Jones A, Ghorbani N, Linz P, Müller DN, Wiegand S, Berger F, Kuehne T, Kelm M. Tissue Sodium Content and Arterial Hypertension in Obese Adolescents. J Clin Med. 2019 Nov 21;8(12):2036.

28

Jain P, Shehab S, Muthiah K, Robson D, Granegger M, Drakos SG, Jansz P, Macdonald PS, Hayward CS. Insights Into Myocardial Oxygen Consumption, Energetics, and Efficiency Under Left Ventricular Assist Device Support Using Noninvasive Pressure-Volume Loops. Circ Heart Fail. 2019 Oct;12(10):e006191.

27

Lee CB, Goubergrits L, Fernandes JF, Nordmeyer S, Knosalla C, Berger F, Falk V, Kuehne T, Kelm M. Surrogates for myocardial power and power efficiency in patients with aortic valve disease. Sci Rep. 2019 Nov 11;9(1):16407.

26

Sutrave S, Kikhney J, Schmidt J, Petrich A, Wiessner A, Kursawe L, Gebhardt M, Kertzscher U, Gabel G, Goubergrits L, Affeld K, Moter A. Effect of daptomycin and vancomycin on Staphylococcus epidermidis biofilms: An in vitro assessment using fluorescence in situ hybridization. PLoS One. 2019 Aug 27;14(8):e0221786.

25

Al-Wakeel-Marquard N, Degener F, Herbst C, Kühnisch J, Dartsch J, Schmitt B, Kuehne T, Messroghli D, Berger F, Klaassen S. RIKADA Study Reveals Risk Factors in Pediatric Primary Cardiomyopathy. J Am Heart Assoc. 2019 Aug 6;8(15):e012531.

24

Berndt N, Patzak A, Holzhütter HG. Metabolic modelling of kidney diseases: Lessons learned from the liver. Acta Physiol (Oxf). 2019 Oct;227(2):e13350.

23

Chitiboi T, Kanski M, Tautz L, Hennemuth A, Halpern D, Sherrid M, Axel L. Analysis of three-chamber view conventional and tagged cine MRI in patients with suspected hypertrophic cardiomyopathy. MAGMA. 2020 Oct;33(5):613-626.

22

Karimkeshteh, S., Kaufhold, L., Nordmeyer, S., Jarmatz, L., Harloff, A., Hennemuth, A. Comparing Subjects with Reference Populations - A Visualization Toolkit for the Analysis of Aortic Anatomy and Pressure Distribution.Springer, Cham. 2019 May30

21

Razafindrazaka, F.H., Vellguth, K., Degener, F., Suendermann, S., Kuehne, T. Mesh Based Approximation of the Left Ventricle Using a Controlled Shrinkwrap Algorithm.Springer, Cham. 2019 May30

20

Wamala I, Brüning J, Dittmann J, Jerichow S, Weinhold J, Goubergritis L, Hennemuth A, Falk V, Kempfert J. Simulation of a Right Anterior Thoracotomy Access for Aortic Valve Replacement Using a 3D Printed Model. Innovations (Phila). 2019 Oct;14(5):428-435.

19

Yevtushenko P, Hellmeier F, Bruening J, Nordmeyer S, Falk V, Knosalla C, Kelm M, Kuehne T, Goubergrits L. Surgical Aortic Valve Replacement: Are We Able to Improve Hemodynamic Outcome? Biophys J. 2019 Dec 17;117(12):2324-2336.

18

Granegger M, Thamsen B, Hubmann EJ, Choi Y, Beck D, Valsangiacomo Buechel E, Voutat M, Schweiger M, Meboldt M, Hübler M. A long-term mechanical cavopulmonary support device for patients with Fontan circulation. Med Eng Phys. 2019 Aug;70:9-18.

17

Daneshgar A, Tang P, Remde C, Lommel M, Moosburner S, Kertzscher U, Klein O, Weinhart M, Pratschke J, Sauer IM, Hillebrandt KH. Teburu-Open source 3D printable bioreactor for tissue slices as dynamic three-dimensional cell culture models. Artif Organs. 2019 Oct;43(10):1035-1041.

16

Vellguth K, Brüning J, Tautz L, Degener F, Wamala I, Sündermann S, Kertzscher U, Kuehne T, Hennemuth A, Falk V, Goubergrits L. User-dependent variability in mitral valve segmentation and its impact on CFD-computed hemodynamic parameters. Int J Comput Assist Radiol Surg. 2019 Oct;14(10):1687-1696.

15

Berndt N, Eckstein J, Heucke N, Gajowski R, Stockmann M, Meierhofer D, Holzhütter HG. Characterization of Lipid and Lipid Droplet Metabolism in Human HCC. Cells. 2019 May 27;8(5):512.

14

Goubergrits L, Kertzscher U, Lommel M. Past and future of blood damage modelling in a view of translational research. Int J Artif Organs. 2019 Mar;42(3):125-132.

13

Berg P, Voß S, Janiga G, Saalfeld S, Bergersen AW, Valen-Sendstad K, Bruening J, Goubergrits L, Spuler A, Chiu TL, Tsang ACO, Copelli G, Csippa B, Paál G, Závodszky G, Detmer FJ, Chung BJ, Cebral JR, Fujimura S, Takao H, Karmonik C, Elias S, Cancelliere NM, Najafi M, Steinman DA, Pereira VM, Piskin S, Finol EA, Pravdivtseva M, Velvaluri P, Rajabzadeh-Oghaz H, Paliwal N, Meng H, Seshadhri S, Venguru S, Shojima M, Sindeev S, Frolov S, Qian Y, Wu YA, Carlson KD, Kallmes DF, Dragomir-Daescu D, Beuing O. Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)-phase II: rupture risk assessment. Int J Comput Assist Radiol Surg. 2019 Oct;14(10):1795-1804.

12

Runte K, Brosien K, Salcher-Konrad M, Schubert C, Goubergrits L, Kelle S, Schubert S, Berger F, Kuehne T, Kelm M. Hemodynamic Changes During Physiological and Pharmacological Stress Testing in Healthy Subjects, Aortic Stenosis and Aortic Coarctation Patients-A Systematic Review and Meta-Analysis. Front Cardiovasc Med. 2019 Apr 10;6:43.

11

Rizk J, Latus H, Shehu N, Mkrtchyan N, Zimmermann J, Martinoff S, Ewert P, Hennemuth A, Stern H, Meierhofer C. Elevated diastolic wall shear stress in regurgitant semilunar valvular lesions. J Magn Reson Imaging. 2019 Sep;50(3):763-770.

10

Harloff A, Hagenlocher P, Lodemann T, Hennemuth A, Weiller C, Hennig J, Vach W. Retrograde aortic blood flow as a mechanism of stroke: MR evaluation of the prevalence in a population-based study. Eur Radiol. 2019 Oct;29(10):5172-5179.

9

Goubergrits L, Hellmeier F, Bruening J, Spuler A, Hege HC, Voss S, Janiga G, Saalfeld S, Beuing O, Berg P. Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): uncertainty quantification of geometric rupture risk parameters. Biomed Eng Online. 2019 Mar 25;18(1):35.

8

Simmonds M, Thamsen B, Kertzscher U. Blood damage in ventricular assist devices. Int J Artif Organs. 2019 Mar;42(3):111-112.

7

Granegger M, Thamsen B, Moscato F, Schlöglhofer T, Gross C, Schneider S, Röhrich M, Kertzscher U, Zimpfer D, Affeld K, Schima H. Noninvasive assessment of blood pressure in rotary blood pump recipients using a novel ultrasonic Doppler method. Int J Artif Organs. 2019 May;42(5):226-232.

6

Neugebauer M, Tautz L, Hüllebrand M, Sündermann S, Degener F, Goubergrits L, Kuehne T, Falk V, Hennemuth A. Virtual downsizing for decision support in mitral valve repair. Int J Comput Assist Radiol Surg. 2019 Feb;14(2):357-371.

5

Razafindrazaka FH, Yevtushenko P, Poelke K, Polthier K, Goubergrits L. Hodge decomposition of wall shear stress vector fields characterizing biological flows. R Soc Open Sci. 2019 Feb 6;6(2):181970.

4

Goubergrits L., Hellmeier F., Neumann D., Mihalef V., Gulsun MA., Chinali M., Secinaro A., Runte K., Schubert S., Berger F., Kuehne T., Hennemuth A., Kelm M. Patient-specific requirements and clinical validation of MRI-based pressure mapping: A two-center study in patients with aortic coarctation. J Magn Reson Imaging. 2019 Jan;49(1):81-89.

3

Hildebrandt T, Brüning JJ, Schmidt NL, Lamecker H, Heppt W, Zachow S, Goubergrits L. The Healthy Nasal Cavity-Characteristics of Morphology and Related Airflow Based on a Statistical Shape Model Viewed from a Surgeon's Perspective. Facial Plast Surg. 2019 Feb;35(1):9-13.

2

Hildebrandt T, Brüning JJ, Lamecker H, Zachow S, Heppt WJ, Schmidt N, Goubergrits L. Digital Analysis of Nasal Airflow Facilitating Decision Support in Rhinosurgery. Facial Plast Surg. 2019 Feb;35(1):3-8.

1

Naci H, Salcher-Konrad M, Mcguire A, Berger F, Kuehne T, Goubergrits L, Muthurangu V, Wilson B, Kelm M. Impact of predictive medicine on therapeutic decision making: a randomized controlled trial in congenital heart disease. NPJ Digit Med. 2019 Mar 19;2:17

Veröffentlichungen 2018

33

Hellmeier F, Nordmeyer S, Yevtushenko P, Bruening J, Berger F, Kuehne T, Goubergrits L, Kelm M. Hemodynamic Evaluation of a Biological and Mechanical Aortic Valve Prosthesis Using Patient-Specific MRI-Based CFD. Artif Organs 2018;42(1):49-57.

32

Fernandes JF, Alves R, Silva TFD, Nordmeyer S, Hellmeier F, Goubergrits L, Hennemuth A, Berger F, Schubert S, Kuehne T, Kelm M.CMR-Based and Time-Shift Corrected Pressure Gradients Provide Good Agreement to Invasive Measurements in Aortic Coarctation.ACC Cardiovasc Imaging 2018;S1936-878X(18):30293-6.

31

Karabelas E, Gsell MA, Augustin CM, Marx L, Neic A, Prassl AJ, Goubergrits L, Kuehne T, Plank G.Towards a computational framework for modeling the impact of aortic coarctations upon left ventricular load.Frontiers in Physiology 2018;9:538.

30

Wehrum T, Guenther F, Fuchs A, Schuchardt F, Hennemuth A, Harloff A. Measurement of cardiac valve and aortic blood flow velocities in stroke patients: a comparison of 4D flow MRI and echocardiographyInt J Cardiovas Imag 2018;34(6).939-946.

29

Zimmermann J, Demedts D, Mirzaee H, Ewert P, Stern H, Meierhofer C, Menze B, Hennemuth A..Wall shear stress estimation in the aorta: Impact of wall motion, spatiotemporal resolution, and phase noise.J Magn Reson Imaging 2018;48(3):718-728.

28

Kaufhold L, Harloff A, Schumann C, Kraff, AJ, Hennig J, Hennemuth A..Image-based assessment of uncertainty in quantification of carotid lumen. In: Elsa, D.A., Bennett, A.L., (Hrsg.) Medical Imaging 2018: Image Processing, SPIE Press 2018 Sep;5(3):034003.

27

Vellguth K, Bruening J, Goubergrits L, Tautz L, Hennemuth A, Kertzscher U, Degener F, Kelm M, Sündermann S, Kuehne T.Development of a modeling pipeline for the prediction of hemodynamic outcome after virtual mitral valve repair using image based CFD.International Journal of Computer Assisted Radiology and Surgery 2018;13(11):1795-1805.

26

Wehrum T, Lodemann T, Hagenlocher P, Stuplich J, Ngo BTT, Grundmann S, Hennemuth A, Hennig J, Harloff A. Age-related changes of right atrial morphology and inflow pattern assessed using 4D flow cardiovascular magnetic resonance: results of a population-based study.J Cardiovasc Magn Reson 2018;20(1):38.

25

Harloff A, Mirzaee H, Lodemann T, Hagenlocher P, Wehrum T, Stuplich J, Hennemuth A, Hennig J, Grundmann S, Vach W.Determination of aortic stiffness using 4D flow cardiovascular magnetic resonance - a population-based study.J Cardiovasc Magn Reson 2018;20(1):43.

24

Tautz L, Neugebauer M, Hüllebrand M, Vellguth K, Degener F, Sündermann S, Wamala I, Goubergrits L, Kuehne T, Falk V, Hennemuth A.Extraction of open-state mitral valve geometry from CT volumes.International Journal of Computer Assisted Radiology and Surgery 2018;13(11):1741-1754.

23

Valen-Sendstad K, Bergersen AW, Shimogonya Y, Goubergrits L et al, Steinman DA..Real-World Variability in the Prediction of Intracranial Aneurysm Wall Shear Stress: The 2015 International Aneurysm CFD Challenge.Journal of Cardiovascular Engineering and Technology 2018;9(4):544-564.

22

Gsell MAF, Augustin CM, Prassl AJ, Karabelas E, Fernandes JF, Kelm M, Goubergrits L, Kuehne T, Plank G..Assessment of wall stresses and mechanical heart power in the left ventricle: Finite element modeling versus Laplace analysis.International Journal for Numerical Methods in Biomedical Engineering 2018;34:e3147.

21

Berg P, Voß S, Saalfeld S, Janiga G, Bergersen AW, Valen-Sendstad K, Bruening J, Goubergrits L, Spuler A et al..Multiple Aneurysms AnaTomy Challenge 2018 (MATCH) - Phase I: Segmentation.Journal of Cardiovascular Engineering and Technology 2018;9(4):565-581.

20

Fernandes JF, Hammel JM, Zhou J, Xiao Y, Chen M, Alves R, Lof J, Grieve SM, Schuster A, Kuehne T, Kutty S..Right ventricular energetics and power in pulmonary regurgitation vs. stenosis using four dimensional phase contrast magnetic resonance.International Journal of Cardiology 2018;263:165-170.

19

Lommel MA, Goubergrits L, Affeld K, Kertzscher U..Couette shearing device for the investigation of shear-induced damage of the primary hemostasis by LVADs.International Journal of Artificial Organs 2018;42(3):143-150.

18

Cho M, Affeld K, Neubauer P, Rechenberg I..Spiders’ Ballooning Flight as a Model for the Exploration of Hazardous Atmospheric Weather Conditions.7th International Conference, Living Machines 2018, Paris, France, July 17–20, 2018, Proceedings 2018;10928:110-114.

17

Bruening J, Hellmeier F, Yevtushenko B, Kuehne T, Goubergrits L.. Uncertainty quantification for non-invasive assessment of pressure drop across a coarctation of the aorta using CFD.Cardiovascular Engineering and Technology 2018;9(4):582-596.

16

Nordmeyer S, Schmitt B, Nasseri B, Alexi-Meskishvili V, Kuehne T, Berger F, Nordmeyer J..Presence of reduced regional left ventricular function even in the absence of left ventricular wall scar tissue in the long term after repair of an anomalous left coronary artery from the pulmonary artery.Cardiol Young 2018;28(2):200-207.

15

Lee DC, Markl M, Dall'Armellina E, Han Y, Kozerke S, Kuehne T, Nielles-Vallespin S, Messroghli D, Patel A, Schaeffter T, Simonetti O, Valente AM, Weinsaft JW, Wright G, Zimmerman S, Schulz-Menger J..The growth and evolution of cardiovascular magnetic resonance: a 20-year history of the Society for Cardiovascular Magnetic Resonance (SCMR) annual scientific sessions.J Cardiovasc Magn Reson 2018;20(1):8.

14

Meyer A, Zverinski D, Pfahringer B, Kempfert J, Kuehne T, Sündermann SH, Stamm C, Hofmann T, Falk V, Eickhoff C..Machine learning for real-time prediction of complications in critical care: a retrospective study.Lancet Respir Med 2018;6(12):905-914.

13

Oliveira RS, Alonso S, Campos FO, Rocha BM, Fernandes JF, Kuehne T, dos Santos RW..Ectopic beats arise from micro-reentries near infarct regions in simulations of a patient-specific heart model.Sci Rep 2018;8(1):16392.

12

Itu L, Neumann D, Mihalef V, Meister F, Kramer M, Gulsun M, Kelm M, Kühne T, Sharma P..Non-invasive assessment of patient-specific aortic haemodynamics from four-dimensional flow MRI data.Interface Focus 2018;8(1):20170006.

11

Berndt N, Holzhütter HG..Dynamic Metabolic Zonation of the Hepatic Glucose Metabolism Is Accomplished by Sinusoidal Plasma Gradients of Nutrients and Hormones.Front Physiol. 2018 Dec 12;9:1786.

10

Berndt N, Rösner J, ul Haq RU, Kann O, Kovács R, Holzhütter HG, Spies C, Liotta A..Possible neurotoxicity of the anesthetic propofol: evidence for the inhibition of complex II of the respiratory chain in area CA3 of rat hippocampal slices.Arch Toxicol 2018;92(10):3191-3205.

9

Kovács R, Gerevich Z, Friedman A, Otáhal J, Prager O, Gabriel S, Berndt N..Bioenergetic Mechanisms of Seizure Control.Front Cell Neurosci 2018;12:335.

8

Granegger M, Schweiger M, Schmid Daners M, Meboldt M, Hübler M..Cavopulmonary mechanical circulatory support in Fontan patients and the need for physiologic control: A computational study with a closed-loop exercise model.Int J Artif Organs 2018;41(5):261-268.

7

Kaufhold L, Goebel H, Mirzaee H, Strecker C, Harloff A, Hennemuth A..Background Correction and Stitching of Histological Plaque Images.Informatik aktuell 2018;Bildverarbeitung für die Medizin 2018:109-114.

6

Ovroutski S, Kramer P, Nordmeyer S, Cho M-Y, Redlin M, Miera O, Photiadis J, Berger F..Early extubation is associated with improved early outcome after extracardiac total cavopulmonary connection independently of duration of cardiopulmonary bypass.Eur J Cardio-Thorac 2018;54(5):953-958.

5

Góreczny S, Dryżek P, Moszura T, Łukaszewski M, Podgórski M, Nordmeyer S, Kühne T, Berger F, Schubert S..Magnetic resonance and computed tomography imaging fusion for live guidance of percutaneous pulmonary valve implantation.Postep Kardiol Inter 2018;14(4):413-421.

4

Thamsen B, Plamondon M, Granegger M, Schmid Daners M, Kaufmann R, Neels A, Meboldt M..Investigation of the Axial Gap Clearance in a Hydrodynamic-Passive Magnetically Levitated Rotary Blood Pump Using X-Ray Radiography.Artificial Organs 2018;42(5):510-515.

3

Nordmeyer S, Murin P, Schulz A, Danne F, Nordmeyer J, Kretzschmar J, Sumbadze D, Schmitt KRL, Miera O, Cho M-Y, Sinzobahamvya N, Berger F, Ovroutski S, Photiadis J..Results of aortic valve repair using decellularized bovine pericardium in congenital surgery.Eur J Cardio-Thorac 2018;54(6):986-992.

2

Stoiber L, Mahfoud F, Zamani SM, Lapinskas T, Böhm M, Ewen S, Kulenthiran S, Schlaich MP, Esler MD, Hammer T, Stensæth KH, Pieske B, Dreysse S, Fleck E, KühneT, Kelm M, Stawowy P, Kelle S..Renal sympathetic denervation restores aortic distensibility in patients with resistant hypertension: data from a multi-center trial.Clin Res Cardiol 2018;107(8):642-652.

1

Bruening J., Hellmeier F., Yevtushenko P., Kelm M., Nordmeyer S., Sündermann S., Kuehne T. & Goubergrits L.. Impact of patient-specific LVOT inflow profiles on aortic valve prosthesis and ascending aorta hemodynamics. J Comput Sci-Neth. 2018;24:91-100.

Veröffentlichungen 2017

20

Fernandes J, Goubergrits L Bruening, J, Hellmeier F, Nordmeyer S, Silva T, Schubert S, Berger F, Kuehne T, Kelm M.Beyond Pressure Gradients: The Effects of Intervention on Heart Power in Aortic Coarctation.PLOS ONE Journal 2017;12(1):e0168487.

19

Salcher M, Mcguire A, Muthurangu V, Kelm M, Kuehne T, Naci H, CARDIOPROOF group.Avoidable costs of stenting for aortic coarctation in the United Kingdom: an economic model.BMC Health Serv Res 2017;17(1):258.

18

Mirzaee H, Henn T, Krause M, Goubergrits L, Schumann C, Neugebauer M, Kuehne T, Preusser T, Hennemuth A.MRI-based computational hemodynamics in patients with aortic coarctation using the lattice Boltzmann methods: Clinical validation study.Journal of Magnetic Resonance Imaging 2017;45(1):139-146.

17

Razafindrazaka FH, Polthier K.Optimal base complexes for quadrilateral meshes.Computer Aided Geometric Design 2017;52-53:63-74.

16

Al-Wakeel-Marquard N, Rastin S, Muench F, OH-Ici D, Yilmaz S, Berger F, Kuehne T, Messroghli DR.Cardiac T1 mapping in congenital heart disease: bolus vs. infusion protocols for measurements of myocardial extracellular volume fraction.Int J Cardiovasc Imaging 2017;33(12):1961–1968.

15

Schüle CY, Affeld K, Kossatz M, Paschereit CO, Kertzscher U.Turbulence measurements in an axial rotary blood pump with laser Doppler velocimetry.The International Journal of Artificial Organs 2017;40(3):109-117.

14

Kelm M, Goubergrits L, Bruening J, Yevtushenko P, Fernandes JF, Sündermann S, Berger F, Falk V, Kuehne T, CARDIOPROOF group, Nordmeyer S.Publisher Correction: Model-Based Therapy Planning Allows Prediction of Haemodynamic Outcome after Aortic Valve Replacement.Nature Scientific Reports 2017;7(1):9897.

13

Huttary R, Goubergrits L, Schütte C, Bernhard S.Simulation, identification and statistical variation in cardiovascular analysis (SISCA) - A software framework for multi-compartment lumped modeling.Computers in Biology and Medicine 2017;87:104-123.

12

Brüning J, Goubergrits L, Heppt W, Zachow S, Hildebrandt T.Numerical Analysis of Nasal Breathing: A Pilot Study.Facial Plast Surg 2017;33(4):388-395.

11

Bruening J, Hellmeier F, Yevtushenko P, Kelm M, Nordmeyer S, Sündermann SH, Kuehne T, Goubergrits L.Impact of patient-specific LVOT inflow profiles on aortic valve prosthesis and ascending aorta hemodynamics.Journal of Computational Science 2017;24:91-100.

10

Goreczny S, Dryzek P, Moszura T, Kühne T, Berger F, Schubert S.3D image fusion for live guidance of stent implantation in aortic coarctation - magnetic resonance imaging and computed tomography image overlay enhances interventional technique.Postep Kardiol Inter 2017;13(3):269-272.

9

Peter P, Kaufhold L, Weickert J.Turning Diffusion-Based Image Colorization Into Efficient Color Compression.IEEE T Image Process 2017;26(2):860-869.

8

Nordmeyer S, Rohder M, Nordmeyer J, Miera O, Peters B, Cho M-J, Photiadis J, Berger F, Ovroutski S.Systemic right ventricular morphology in the early postoperative course after extracardiac Fontan operation: is there still a need for special care?.Eur J Cardio-Thorac 2017;51(3):483-489.

7

Zoehrer F, Huellebrand M, Chitiboi T, Oechtering T, Sieren M, Frahm J, Hahn H, Hennemuth A.Real-time myocardium segmentation for the assessment of cardiac function variation.SPIE Press 2017;10137:101370L.

6

Yevtushenko P, Hellmeier F, Bruening J, Kuehne T, Goubergrits L.Numerical investigation of the impact of branching vessel boundary conditions on aortic hemodynamics.Curr Dir Biomed Eng 2017;3(2):321-324.

5

Chitiboi T, Ramb R, Feng L, Piekarski E, Tautz L, Hennemuth A, Axel L.Multi-cycle Reconstruction of Cardiac MRI for the Analysis of Inter-ventricular Septum Motion During Free Breathing.Lect Notes Comput Sc 2017;10263:63-72.

4

Wehrum T, Dragonu I, Strecker C, Schuchardt F, Hennemuth A, Drexl J, Reinhard T, Böhringer D, Vach W, Henning J, Harloff A.Aortic atheroma as a source of stroke - assessment of embolization risk using 3D CMR in stroke patients and controls.J Cardiovasc Magn Reson 2017;19(1):67.

3

Pontre B, Cowan BR, DiBella E, Kulaseharan S, Likhite D, Noorman N, Tautz L, Tustison N, Wollny G, Young AA, Suinesiaputra A.An Open Benchmark Challenge for Motion Correction of Myocardial Perfusion MRI.IEEE J Biomed Health 2017;21(5):1315-1326.

2

Schuchardt F, Hennemuth A, Schroeder L, Meckel S, Markl M, Wehrum T, Harloff A.Acute Cerebral Venous Thrombosis: Three-Dimensional Visualization and Quantification of Hemodynamic Alterations Using 4-Dimensional Flow Magnetic Resonance Imaging.Stroke 2017;48(3):671-677.

1

Messroghli DR, Pickardt T, Fischer M, Opgen-Rhein B, Papakostas K, Böcker D, Jakob A, Khalil M, Mueller GC, Schmidt F, Kaestner M, Udink Ten Cate FEK, Wagner R, Ruf B, Kiski D, Wiegand G, Degener F, Bauer UMM, Friede T, Schubert S, MYKKE Consortium.Toward evidence-based diagnosis of myocarditis in children and adolescents: Rationale, design, and first baseline data of MYKKE, a multicenter registry and study platform.American Heart Journal 2017;187:133-144.